Roberts D C, Huff M W, Carroll K K
Nutr Metab. 1979;23(6):476-86. doi: 10.1159/000176294.
Rabbits were weaned to different semipurified diets to determine which characteristics of the diet were required to maintain the hypercholesterolemia of the suckling period. Gradual weaning to a diet similar in fat, cholesterol, protein and carbohydrate content to rabbit milk maintained and enhanced the hypercholesterolemia. Reduction of the cholesterol content, and to some extent the fat content of this diet, decreased the plasma cholesterol level, but the type of dietary protein did not alter the results. After weaning, however, animals fed milk protein (casein) in the absence of dietary cholesterol became hypercholesterolemic, whereas those fed plant protein (soy protein isolate) remained normocholesterolemic.
将兔子断奶后喂食不同的半纯化日粮，以确定维持哺乳期高胆固醇血症所需的日粮特性。逐渐断奶至脂肪、胆固醇、蛋白质和碳水化合物含量与兔奶相似的日粮，可维持并加重高胆固醇血症。降低该日粮的胆固醇含量，以及在一定程度上降低脂肪含量，可降低血浆胆固醇水平，但日粮蛋白质的类型并未改变结果。然而，断奶后，在无日粮胆固醇的情况下喂食乳蛋白（酪蛋白）的动物出现高胆固醇血症，而喂食植物蛋白（大豆分离蛋白）的动物仍保持正常胆固醇水平。
