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高压氧治疗下肢静脉曲张性溃疡

The treatment of varicose leg ulcers by hyperbaric oxygen.

作者信息

Bass B H

出版信息

Postgrad Med J. 1970 Jul;46(537):407-8. doi: 10.1136/pgmj.46.537.407.

DOI:10.1136/pgmj.46.537.407
PMID:5476140
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2467052/
Abstract

Hyperbaric oxygen at 2 atmospheres pressure was administered to nineteen cases of chronic varicose leg ulceration. Treatment was given for 2 hr on 5 days of each week. Bacterial infection of the ulcers was suppressed, and drying of the lesions occurred within hours of commencing treatment. Epithelialization of healthy granulation tissue was a constant feature. Simple venous ulcers consistently responded better than those cases where arterial insufficiency was present. No adverse reactions were observed. Seventeen of the nineteen patients had their ulcers healed after a mean exposure to OHP of 60·7 hr.

摘要

对19例慢性下肢静脉曲张性溃疡患者进行了2个大气压的高压氧治疗。每周治疗5天,每次治疗2小时。溃疡的细菌感染得到抑制,治疗开始后数小时内溃疡面干燥。健康肉芽组织上皮化是持续出现的特征。单纯性静脉溃疡的疗效始终优于存在动脉供血不足的病例。未观察到不良反应。19例患者中有17例在平均接受60.7小时的高压氧治疗后溃疡愈合。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fca/2467052/c3cc93b07e2b/postmedj00355-0007-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fca/2467052/60efbe26bf70/postmedj00355-0007-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fca/2467052/c3cc93b07e2b/postmedj00355-0007-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fca/2467052/60efbe26bf70/postmedj00355-0007-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fca/2467052/c3cc93b07e2b/postmedj00355-0007-b.jpg

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1
The treatment of varicose leg ulcers by hyperbaric oxygen.高压氧治疗下肢静脉曲张性溃疡
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引用本文的文献

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Hyperbaric Oxygen Therapy Is an Effective Adjunctive Therapy to Manage Treatment-Resistant Venous Leg Ulcers.高压氧疗法是治疗难愈性下肢静脉溃疡的一种有效辅助疗法。
Ann Vasc Dis. 2021 Sep 25;14(3):273-276. doi: 10.3400/avd.cr.21-00030.
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Hyperbaric Oxygen Therapy for Venous Leg Ulcers: A 6 Year Retrospective Study of Results of a Single Center.高压氧疗法治疗下肢静脉溃疡:单中心6年结果回顾性研究
Front Med (Lausanne). 2021 Jul 28;8:671678. doi: 10.3389/fmed.2021.671678. eCollection 2021.
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Oxygen modulates the growth of skin fibroblasts.

本文引用的文献

1
Near-avulsion of foot treated by replacement and subsequent prolonged exposure of patient to oxygen at two atmospheres pressure.足部近乎撕脱伤,采用复位治疗,随后让患者在两个大气压下长时间吸氧。
Lancet. 1961 Nov 18;2(7212):1122-3. doi: 10.1016/s0140-6736(61)91031-5.
2
Topical hyperbaric oxygen treatment of pressure sores and skin ulcers.
Lancet. 1969 Aug 23;2(7617):405-9. doi: 10.1016/s0140-6736(69)90113-5.
氧气调节皮肤成纤维细胞的生长。
In Vitro Cell Dev Biol Anim. 2002 May;38(5):305-10. doi: 10.1290/1071-2690(2002)038<0305:OMTGOS>2.0.CO;2.
4
Hyperbaric oxygen treatment in the Royal Air Force.英国皇家空军的高压氧治疗
Proc R Soc Med. 1971 Sep;64(9):881-2. doi: 10.1177/003591577106400905.