Monin G, Sellier P, Ollivier L
Ann Rech Vet. 1979;10(4):535-47.
Lactic acid, glucose, creatine phosphokinase (CPK) and some mineral components were determined in the blood of piglets before and after a halothane test of five minutes (only before for CPK). Two different experimental groups were studied: 222 Pietrain piglets from an INRA experimental herd, and 325 piglets from the Large White, French Landrace and Belgian Landrace breeds entering performance testing stations. Animals reacting positively to halothane ("MHS" piglets) have significantly higher blood levels of lactic acid and potassium before anesthesia than normal animals. CPK is also higher, except for the Belgian Landrace: in this breed CPK shows the same average value and distribution in the two groups of piglets (normal and MHS). There are also breed differences in blood magnesium, independently of the reaction to halothane. But the breed differences observed in lactic acid and CPK are related to the proportion of MHS piglets in each breed. Anesthesia by means of halothane lowers the measured blood characteristics--except for glucose--in normal animals, and rises them--except for potassium--in MHS piglets. The results are discussed in view of the incomplete discrimination between the two types of pigs, with a 5 minutes test, and, particularly, considering possible breed differences in that respect.
在对仔猪进行5分钟氟烷测试之前和之后（仅在测试前测定肌酸磷酸激酶CPK），测定了仔猪血液中的乳酸、葡萄糖、肌酸磷酸激酶（CPK）和一些矿物质成分。研究了两个不同的实验组：来自法国国家农业研究院实验猪群的222头皮特兰仔猪，以及进入性能测试站的325头大白猪、法国长白猪和比利时长白猪品种的仔猪。对氟烷反应呈阳性的动物（“MHS”仔猪）在麻醉前血液中的乳酸和钾水平明显高于正常动物。CPK也较高，但比利时长白猪除外：在该品种中，两组仔猪（正常和MHS）的CPK平均值和分布相同。血液中的镁含量也存在品种差异，与对氟烷的反应无关。但观察到的乳酸和CPK的品种差异与每个品种中MHS仔猪的比例有关。氟烷麻醉会降低正常动物血液中所测特征（葡萄糖除外），而会升高MHS仔猪血液中所测特征（钾除外）。鉴于在5分钟测试中对两种类型猪的区分不完全，特别是考虑到这方面可能存在的品种差异，对结果进行了讨论。
