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住院慢性精神分裂症患者和癫痫患者血清的定量免疫电泳分析

Quantitative immunoelectrophoresis of serum from hospitalized chronic schizophrenic and epileptic patients.

作者信息

Clarke H G, Freeman T, Pryse-Phillips W

出版信息

J Neurol Neurosurg Psychiatry. 1970 Oct;33(5):694-7. doi: 10.1136/jnnp.33.5.694.

DOI:10.1136/jnnp.33.5.694
PMID:5478952
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC493551/
Abstract

Ten serum proteins are measured by quantitative immunoelectrophoresis in 20 chronic schizophrenic and nine epileptic patients. Results from each group are compared with each other and with normal values and significant differences noted. Schizophrenic patients had higher haemopexin levels and epileptic patients had higher α2 group component levels, both compared with normal subjects. Also schizophrenics had higher αPG(p) and α(1)AT levels compared with epileptics.

摘要

通过定量免疫电泳对20名慢性精神分裂症患者和9名癫痫患者的10种血清蛋白进行了测量。将每组的结果相互比较，并与正常值进行比较，记录显著差异。与正常受试者相比，精神分裂症患者的血红素结合蛋白水平较高，癫痫患者的α2组成分水平较高。此外，与癫痫患者相比，精神分裂症患者的αPG(p)和α(1)AT水平较高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83ad/493551/a63ef1e5f85b/jnnpsyc00221-0143-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83ad/493551/a63ef1e5f85b/jnnpsyc00221-0143-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83ad/493551/a63ef1e5f85b/jnnpsyc00221-0143-a.jpg

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本文引用的文献

1
Studies on the role of ceruloplasmin in schizophrenia.关于铜蓝蛋白在精神分裂症中作用的研究。
Int Rev Neurobiol. 1959;1:333-42. doi: 10.1016/s0074-7742(08)60319-0.
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ANTIGEN-ANTIBODY CROSSED ELECTROPHORESIS.抗原-抗体交叉电泳
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The schizophrenialike psychoses of epilepsy.癫痫所致的精神分裂症样精神病
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Serum lipoprotein concentrations in a schizophrenic population.精神分裂症患者群体中的血清脂蛋白浓度
Am J Psychiatry. 1957 Sep;114(3):263-5. doi: 10.1176/ajp.114.3.263.
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Comparative study of blood ceruloplasmin in schizophrenia and other disorders.精神分裂症及其他疾病中血铜蓝蛋白的比较研究。
AMA Arch Neurol Psychiatry. 1957 Jun;77(6):643-5. doi: 10.1001/archneurpsyc.1957.02330360101011.
9
Elevation of serum protein-bound carbohydrates and haptoglobin in schizophrenia.精神分裂症患者血清蛋白结合碳水化合物和触珠蛋白水平升高。
Clin Chem. 1966 Oct;12(10):709-16.
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Quantitative immunoelectrophoresis of human serum proteins.人血清蛋白的定量免疫电泳
Clin Sci. 1968 Oct;35(2):403-13.