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器官磷脂对体外培养胚胎组织生长的影响。

Effect of organ phospholipids on the growth of embryonal tissues cultured in vitro.

作者信息

Cocchi M, Marzona L, Pignatti C, Olivo O M

出版信息

Biochem Exp Biol. 1979;15(1):13-6.

PMID:548116
Abstract

With regard to a set of studies about cellular nutrition, the effect of different amounts of phospholipids, extracted from various organs of calf (diencephalon, retina, cerebral cortex and heart), on normal embryonal chicken myocardium cultures has been tested. From the numerous observations we have made it is resulted that phospholipids, particularly at the highest levels, constantly decrease the culture migration velocity and this reduction is remarkably more accentuated in presence of 1.25%(0) heart phospholipids. Moreover in this condition the cells show a change in their morphology and appear all full of big lipid drops, perhaps in consequence of an alteration of the chemical-physical plasmalemma characteristics and a change in the membrane enzyme activities involving lipid metabolism too.

摘要

关于一组细胞营养研究,已测试了从小牛不同器官(间脑、视网膜、大脑皮层和心脏)提取的不同量磷脂对正常胚胎鸡心肌培养物的影响。从我们所做的大量观察结果来看,磷脂,尤其是在最高水平时,会持续降低培养物的迁移速度,并且在存在1.25%(0)心脏磷脂的情况下,这种降低更为明显。此外,在这种情况下,细胞的形态会发生变化,并且似乎都充满了大的脂滴,这可能是由于化学物理性质的质膜特性发生改变以及涉及脂质代谢的膜酶活性发生变化所致。

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1
Effect of organ phospholipids on the growth of embryonal tissues cultured in vitro.器官磷脂对体外培养胚胎组织生长的影响。
Biochem Exp Biol. 1979;15(1):13-6.
2
Biometabolic effects of different nutrients on embryonal cultures.不同营养物质对胚胎培养的生物代谢影响。
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