Ruckley C V, Das P C, Leitch A G, Donaldson A A, Copland W A, Redpath A T, Scott P, Cash J D
Br Med J. 1970 Nov 14;4(5732):395-8. doi: 10.1136/bmj.4.5732.395.
A total of 76 "high-risk" surgical patients were studied for evidence of venous thromboembolic disease. Episodes of deep vein thrombosis and of pulmonary embolism were related to changes in blood levels of fibrin degradation products (F.D.P.). When diagnosed either by ordinary clinical means or by venography and isotope scanning significantly raised F.D.P. levels were found in all cases. Serum F.D.P. estimations are unlikely to help in detecting deep vein thrombosis, but may prove valuable in diagnosing pulmonary embolism.
对76例“高危”外科手术患者进行了静脉血栓栓塞性疾病证据的研究。深静脉血栓形成和肺栓塞发作与纤维蛋白降解产物（F.D.P.）血液水平的变化有关。当通过普通临床手段或静脉造影及同位素扫描诊断时，所有病例均发现F.D.P.水平显著升高。血清F.D.P.测定不太可能有助于检测深静脉血栓形成，但可能在诊断肺栓塞方面证明有价值。
