Kraft-Kinz J, Prexl H J
Langenbecks Arch Chir. 1975 Nov;339:276-81.
In 1898 the first radical operation for carcinoma of the pancreas was performed by Codivilla in Bologna. Kausch followed in 1913 and Whipple perfected the technique of duodenopancreatectomy. The central position of the pancreas causes technical difficulties. Carcinoma of the head of the pancreas frequently causes icterus, which quite often limits the primary radical operation. Radical removal of carcinoma of the head of the pancreas is only possible if the limits of the organ have not been passed. Preservation of a part of the pancreas is essential for the metabolism. The average primary mortality of the radical operation is around 25 percent, having fallen significantly in the last few years. The 5-years recovery rate is a bare 10 percent.
1898年，博洛尼亚的科迪维拉首次对胰腺癌实施了根治性手术。1913年考施开展了相关手术，惠普尔完善了十二指肠胰腺切除术技术。胰腺的中心位置导致手术存在技术难题。胰头癌常引发黄疸，这常常限制了初次根治性手术。只有在未超出器官界限时，才有可能对胰头癌进行根治性切除。保留部分胰腺对新陈代谢至关重要。根治性手术的平均初次死亡率约为25%，在过去几年中已显著下降。5年康复率仅为10%。
