Trede M, Kersting K H, Hoffmeister A
MMW Munch Med Wochenschr. 1977 May 6;119(18):617-22.
89 cases of pancreatic or periampullary carcinoma were analysed and the following problems discussed: 1.
"early" diagnosis is at present impossible--not even with E.R.C.P. or angiography, although these provide valuable information for planning the operation. 2. Indication for operation: a curative resection was possible in only 20% of cases. The apparent advantages of total pancreatectomy as against the conventional Whipple operation (increased radicality and reduced post-op. complications) have not yet paid off in terms of improved long-term survival. 3.
in 46 pancreato-duodenectomies (for carcinoma as well as complicated chronic pancreatitis) the operative and hospital mortality was 4.3%.
对89例胰腺癌或壶腹周围癌进行了分析，并讨论了以下问题：1. 诊断：目前尚无法进行“早期”诊断——即便使用内镜逆行胰胆管造影（ERCP）或血管造影术也不行，尽管这些检查可为手术规划提供有价值的信息。2. 手术指征：仅20%的病例可行根治性切除。全胰切除术相对于传统的惠普尔手术的明显优势（更高的根治性和更低的术后并发症）在改善长期生存率方面尚未得到体现。3. 结果：在46例胰十二指肠切除术（用于治疗癌症以及复杂的慢性胰腺炎）中，手术死亡率和住院死亡率为4.3%。
