影响红色青霉Stoll产生红曲霉素B的环境和营养因素。
Environmental and nutritional factors affecting the production of rubratoxin B by Penicillium rubrum Stoll.
作者信息
Hayes A W, Wyatt E P, King P A
出版信息
Appl Microbiol. 1970 Sep;20(3):469-73. doi: 10.1128/am.20.3.469-473.1970.
Abstract
Rubratoxin B can be produced in a semisynthetic medium by Penicillium rubrum under varying environmental and nutritional conditions. Maximum production (552.0 mg/500 ml) was obtained with P. rubrum NRRL A-11785 grown in stationary cultures of Mosseray's simplified Raulin solution supplemented with 2.5% malt extract broth at ambient temperature. Zinc is required at levels of at least 0.4 mg per liter. In the absence of iron sulfate, there was a 50-fold reduction in rubratoxin B production but not in growth. No toxin was produced by this isolate in 5- or 7-liter fermentors.
摘要
在不同的环境和营养条件下，红色青霉可在半合成培养基中产生红天精毒素B。在室温下，将红色青霉NRRL A-11785接种于添加了2.5%麦芽提取物肉汤的简化莫塞雷劳林溶液静止培养物中，可获得最大产量（552.0毫克/500毫升）。锌的需求量至少为每升0.4毫克。在没有硫酸亚铁的情况下，红天精毒素B的产量降低了50倍，但生长不受影响。该菌株在5升或7升发酵罐中不产生毒素。
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