Ueno Y, Ishikawa I
Appl Microbiol. 1969 Sep;18(3):406-9. doi: 10.1128/am.18.3.406-409.1969.
Various factors affecting the yields of luteoskyrin, a hepatotoxic mycotoxin, and related pigments in the liquid medium were studied. Maximal yields of luteoskyrin (0.13% by isolation) and of other pigments were attained in the late phase of the cultivation. The yield of the pigment was increased by supplying malt extract, malonic acid, glutamic acid, or asparagine. A useful material for preparation of (14)C-labeled luteoskyrin was 2-(14)C-malonate.
研究了影响肝毒性霉菌毒素黄天精及其相关色素在液体培养基中产量的各种因素。黄天精(分离得到的含量为0.13%)和其他色素的最大产量在培养后期获得。通过添加麦芽提取物、丙二酸、谷氨酸或天冬酰胺可提高色素产量。制备(14)C标记黄天精的有用原料是2-(14)C-丙二酸盐。