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关于兔和人麝香草酚的代谢解毒作用。

On the metabolic detoxication of thymol in rabbit and man.

作者信息

Takada M, Agata I, Sakamoto M, Yagi N, Hayashi N

出版信息

J Toxicol Sci. 1979 Nov;4(4):341-50. doi: 10.2131/jts.4.341.

DOI:10.2131/jts.4.341
PMID:548583
Abstract

The metabolic detoxication of thymol was investigated in rabbit and man. Thymol glucuronide which the aglycone is intact, was isolated from thymol medicated rabbit urine and identified as a acetyl derivative of methyl glucuronate. The hydroxylated product of thymol, thymohydroquinone, was recognized in a small amount in thymol medicated human urine. It was presumed that thymohydroquinone is excreted as ethereal sulfuric acid conjugate in man.

摘要

在兔子和人体中研究了百里酚的代谢解毒作用。从用百里酚处理过的兔子尿液中分离出糖苷配基完整的百里酚葡糖醛酸苷,并鉴定为甲基葡糖醛酸的乙酰衍生物。在服用百里酚的人体尿液中发现了少量百里酚的羟基化产物对甲酚氢醌。据推测,对甲酚氢醌在人体中以硫酸醚共轭物的形式排泄。

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Metabolism of labetalol by animals and man.拉贝洛尔在动物和人体内的代谢。
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Dynamics of thymol dietary supplementation in quail (Coturnix japonica): Linking bioavailability, effects on egg yolk total fatty acids and performance traits.百里香酚日粮补充对鹌鹑(Coturnix japonica)的影响:生物利用度、对蛋黄总脂肪酸和生产性能的关联。
PLoS One. 2019 May 9;14(5):e0216623. doi: 10.1371/journal.pone.0216623. eCollection 2019.
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