饥饿期间分离的大鼠肝细胞核中核糖核酸合成减少。
Decreased ribonucleic acid synthesis in isolated rat liver nuclei during starvation.
作者信息
Rickwood D, Klemperer H G
出版信息
Biochem J. 1970 Nov;120(2):381-4. doi: 10.1042/bj1200381.
Abstract
- Isolated nuclei from starved rats showed a lowered incorporation of [(14)C]UMP into RNA. 2. The Mg(2+)-dependent incorporation was decreased by 30% after 1 day of starvation, but incorporation in the presence of Mn(2+) and ammonium sulphate decreased only after longer periods of starvation. 3. RNA synthesis by nuclei in the presence of excess of added RNA polymerase was unchanged after 1 day of starvation and was inhibited by 20% after 4 days. 4. The capacity of nuclei to bind actinomycin D was unchanged after 1 day and was decreased by 20% after 4 days of starvation.
摘要
- 来自饥饿大鼠的分离细胞核显示[(14)C]UMP掺入RNA的量降低。2. 饥饿1天后，Mg(2+)依赖性掺入减少了30%，但在Mn(2+)和硫酸铵存在下的掺入仅在饥饿较长时间后才减少。3. 在添加过量RNA聚合酶的情况下，细胞核的RNA合成在饥饿1天后没有变化，在饥饿4天后受到20%的抑制。4. 细胞核结合放线菌素D的能力在饥饿1天后没有变化，在饥饿4天后降低了20%。
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本文引用的文献
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