γ-氨基丁酸与海马体抑制作用
GABA and hippocampal inhibition.
作者信息
Curtis D R, Felix D, McLellan H
出版信息
Br J Pharmacol. 1970 Dec;40(4):881-3. doi: 10.1111/j.1476-5381.1970.tb10663.x.
Abstract
Bicuculline, a specific GABA antagonist, diminishes basket cell inhibition of hippocampal pyramidal neurones, an inhibition which is not affected by strychnine.The inhibitory transmitter released by basket cells is thus probably GABA.
摘要
荷包牡丹碱是一种特异性γ-氨基丁酸（GABA）拮抗剂，它会减弱篮状细胞对海马锥体神经元的抑制作用，而这种抑制作用不受士的宁影响。因此，篮状细胞释放的抑制性递质可能是GABA。
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