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Indomethacin-induced intestinal lesions in the rat.

作者信息

Brodie D A, Cook P G, Bauer B J, Dagle G E

出版信息

Toxicol Appl Pharmacol. 1970 Nov;17(3):615-24. doi: 10.1016/0041-008x(70)90036-0.

DOI:10.1016/0041-008x(70)90036-0
PMID:5495986
Abstract
摘要

相似文献

1
Indomethacin-induced intestinal lesions in the rat.吲哚美辛诱导的大鼠肠道损伤
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Effects of cholestyramine and synthetic hydrotalcite on acute gastric or intestinal lesion formation in rats and dogs.
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Small intestinal ulcers and intestinal flora in rats given indomethacin.给予吲哚美辛的大鼠的小肠溃疡与肠道菌群
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4
The effect of gastric cytoprotective drugs (atropine, cimetidine, vitamin-A) on the indomethacin induced intestinal ulcers in rats.胃细胞保护药物（阿托品、西咪替丁、维生素A）对消炎痛诱导的大鼠肠道溃疡的影响。
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Letter: Inhibitory effect of cholestyramine on the intestinal ulcer formation in rats given an antiphlogistic agent.
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Dopamine-induced protection against indomethacin-evoked intestinal lesions in rats--role of anti-intestinal motility mediated by D2 receptors.多巴胺对吲哚美辛诱发的大鼠肠道损伤的保护作用——D2受体介导的抗肠道运动的作用
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[Intestinal ulcer due to indomethacin].
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Relationship of the enterohepatic cycle to ulcerogenesis in the rat small bowel with flufenamic acid.
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NSAID-Associated Small Intestinal Injury: An Overview From Animal Model Development to Pathogenesis, Treatment, and Prevention.非甾体抗炎药相关性小肠损伤：从动物模型建立到发病机制、治疗及预防的概述
Front Pharmacol. 2022 Feb 9;13:818877. doi: 10.3389/fphar.2022.818877. eCollection 2022.
2
NSAID-Induced Enteropathy Affects Regulation of Hepatic Glucose Production by Decreasing GLP-1 Secretion.非甾体抗炎药诱导的肠病通过减少 GLP-1 分泌影响肝脏葡萄糖生成的调节。
Nutrients. 2021 Dec 28;14(1):120. doi: 10.3390/nu14010120.
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Therapeutic and Preventive Effects of Extract on Indomethacin-Induced Small Intestinal Injury Model in Rats.
提取物对吲哚美辛诱导的大鼠小肠损伤模型的治疗和预防作用
Evid Based Complement Alternat Med. 2020 Dec 23;2020:6669813. doi: 10.1155/2020/6669813. eCollection 2020.
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Indomethacin increases severity of Clostridium difficile infection in mouse model.吲哚美辛会增加艰难梭菌感染小鼠模型的严重程度。
Future Microbiol. 2018 Sep;13(11):1271-1281. doi: 10.2217/fmb-2017-0311. Epub 2018 Sep 21.
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Pretreatment with indomethacin results in increased heat stroke severity during recovery in a rodent model of heat stroke.吲哚美辛预处理会导致热射病模型大鼠复温期热射病严重程度增加。
J Appl Physiol (1985). 2017 Sep 1;123(3):544-557. doi: 10.1152/japplphysiol.00242.2017. Epub 2017 Jun 8.
6
Indomethacin injury to the rat small intestine is dependent upon biliary secretion and is associated with overgrowth of enterococci.吲哚美辛对大鼠小肠的损伤依赖于胆汁分泌，并与肠球菌过度生长有关。
Physiol Rep. 2016 Mar;4(6). doi: 10.14814/phy2.12725. Epub 2016 Mar 31.
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Bidirectional interactions between indomethacin and the murine intestinal microbiota.吲哚美辛与小鼠肠道微生物群之间的双向相互作用。
Elife. 2015 Dec 23;4:e08973. doi: 10.7554/eLife.08973.
8
In vitro evidence that phosphatidylcholine protects against indomethacin/bile acid-induced injury to cells.体外证据表明磷脂酰胆碱可预防消炎痛/胆酸诱导的细胞损伤。
Am J Physiol Gastrointest Liver Physiol. 2015 Feb 1;308(3):G217-22. doi: 10.1152/ajpgi.00322.2014. Epub 2014 Dec 4.
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Mutual Amide Prodrug of Etodolac-glucosamine: Synthesis, Characterization and Pharmacological Screening.依托度酸-葡萄糖胺互酰胺前药：合成、表征及药理筛选
Indian J Pharm Sci. 2013 Jul;75(4):406-12. doi: 10.4103/0250-474X.119813.
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The pharmacology of fenbufen, 3-(4-biphenylylcarbonyl)propionic acid, and 4-biphenylacetic acid, interesting antiinflammatory-analgesic agents.芬布芬、3-(4-联苯基羰基)丙酸和 4-联苯乙酸的药理学研究，这些都是有趣的抗炎-镇痛药物。
Inflammation. 1976 Dec;1(4):415-38. doi: 10.1007/BF00920340.