脑循环中血流量与流速的关系。
Relationship between volume flow and velocity in the cerebral circulation.
作者信息
Rowan J O, Harper A M, Miller J D, Tedeschi G M, Jennett W B
出版信息
J Neurol Neurosurg Psychiatry. 1970 Dec;33(6):733-8. doi: 10.1136/jnnp.33.6.733.
Abstract
The relationship between the velocity of the cerebral circulation and the cerebral blood flow was explored at varying levels of PaCO(2), systemic arterial pressure, intracranial pressure, and perfusion pressure, using radioisotope techniques in baboons. Only at low flow rates did velocity increase with flow, and then non-linearly; at high rates velocity increased progressively less. Changes in flow are reflected by changes in velocity in such restricted circumstances that mean circulation time is a very unreliable indication of cerebral blood flow.
摘要
利用放射性同位素技术，在不同的动脉血二氧化碳分压、体循环动脉压、颅内压和灌注压水平下，对狒狒脑循环速度与脑血流量之间的关系进行了研究。仅在低流速时，速度才随流量增加，且呈非线性增加；在高流速时，速度增加逐渐减少。在这种受限情况下，流量变化由速度变化反映出来，以至于平均循环时间作为脑血流量的指标非常不可靠。
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