Suppr超能文献

灵长类动物实验性脑受压期间的颅内容积-压力关系。1. 对脑室容积变化的压力反应。

Intracranial volume--pressure relationships during experimental brain compression in primates. 1. Pressure responses to changes in ventricular volume.

作者信息

Leech P, Miller J D

出版信息

J Neurol Neurosurg Psychiatry. 1974 Oct;37(10):1093-8. doi: 10.1136/jnnp.37.10.1093.

Abstract

Intermittent additions of 0·05 ml saline were made into the lateral ventricle of anaesthetized, ventilated baboons at regular intervals during continuous inflation of a supratentorial extradural balloon. Close correlation was observed both between the increase in ventricular fluid pressure (VFP) immediately after the injection and the volume in the balloon (P < 0·001); and between the increase in ventricular pressure and the pressure immediately before the injection (P < 0·001). This change in ventricular fluid pressure, which is termed the volume-pressure response (VPR), helps to delineate the stage reached on the intracranial volume-pressure curve, and is therefore a measure of the capacity of the intracranial contents to compensate for the volume changes produced by an expanding intracranial lesion. The VPR is currently being used in patients and the clinical implications of confirming its validity experimentally are therefore discussed.

摘要

在幕上硬膜外球囊持续充气过程中,定期向麻醉通气的狒狒侧脑室内间歇性注入0.05毫升生理盐水。注射后即刻的脑室液压力(VFP)升高与球囊内体积之间观察到密切相关性(P < 0.001);脑室压力升高与注射前即刻的压力之间也观察到密切相关性(P < 0.001)。这种脑室液压力的变化,称为容积-压力反应(VPR),有助于确定颅内容积-压力曲线上所达到的阶段,因此是颅内内容物补偿颅内病变扩展所产生的容积变化能力的一种度量。目前VPR正在患者中使用,因此讨论了通过实验证实其有效性的临床意义。

相似文献

引用本文的文献

10

本文引用的文献

3
Blood gas calculator.血气计算器。
J Appl Physiol. 1966 May;21(3):1108-16. doi: 10.1152/jappl.1966.21.3.1108.
5
Relationship between volume flow and velocity in the cerebral circulation.脑循环中血流量与流速的关系。
J Neurol Neurosurg Psychiatry. 1970 Dec;33(6):733-8. doi: 10.1136/jnnp.33.6.733.
6
Increased intracranial pressure.颅内压升高。
Clin Neurosurg. 1969;16:436-71. doi: 10.1093/neurosurgery/16.cn_suppl_1.436.
8
The pressure-volume curve of the cerebrospinal fluid space in dogs.犬脑脊液腔的压力-容积曲线
Acta Neurol Scand. 1973;49(5):557-74. doi: 10.1111/j.1600-0404.1973.tb01330.x.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验