Kanajet D
Jugosl Ginekol Opstet. 1979;19(1-2):67-72.
A melanoma of the uterine cervix, 4 mm in diameter, considered primary, in a 44-year-old pluripara is described. She was subjected to hysterectomy coupled with adnexectomy and also to BCG immunotherapy. A year following the beginning of the therapy she is without any symptom of the disease. The rarity of the tumour in this localization is pointed out, and a short review is given of the cases reported in the literature, including those of benign melanosis and "blue nevus". The histogenesis and cytologic diagnosis are discussed, as well as therapeutic possibilities. Emphasis is laid on the varying biological behaviour of the tumour which prevents the assessment of the therapy with regard to the possibility of a very late development of metastases.
本文描述了一名44岁经产妇,患有直径4毫米的原发性子宫颈黑色素瘤。她接受了子宫切除术加附件切除术,并接受了卡介苗免疫治疗。治疗开始一年后,她没有任何疾病症状。文中指出了该部位肿瘤的罕见性,并对文献报道的病例进行了简要回顾,包括良性黑色素沉着症和“蓝色痣”的病例。讨论了组织发生学、细胞学诊断以及治疗可能性。强调了肿瘤生物学行为的差异,这使得难以根据转移灶极晚出现的可能性来评估治疗效果。