Visser A A, Giesteira M V, Prinsloo S T
S Afr Med J. 1979 Sep 1;56(12):481-4.
The effectiveness of beta 2-adrenergic stimulants as suppressants of active labour is well known. This study examines the effects of salbutamol upon established labour in 32 patients undergoing emergency caesarean section. Twenty-five (78,1%) of the patients studied showed a sustained and effective suppression of labour after a bolus intravenous injection of 250 micrograms salbutamol. In 6 of the 7 remaining patients the parameters of uterine activity were also dramatically decreased, but because uterine activity recurred, it had to be further suppressed with an intravenous infusion. There was only 1 refractory case. No serious maternal or fetal side-effects were noted, and patient acceptance was good.
β2 - 肾上腺素能兴奋剂作为活跃分娩抑制剂的有效性是众所周知的。本研究考察了沙丁胺醇对32例行急诊剖宫产患者已确立的分娩过程的影响。在研究的患者中,25例(78.1%)在静脉推注250微克沙丁胺醇后分娩得到持续且有效的抑制。其余7例患者中有6例子宫活动参数也显著降低,但由于子宫活动复发,不得不通过静脉输注进一步抑制。仅1例难治性病例。未观察到严重的母体或胎儿副作用,患者接受度良好。