Barta L, Simon S, Csaba A
Acta Paediatr Acad Sci Hung. 1979;20(4):359-63.
In the parents of 250 diabetic children the occurrence of juvenile and maturity onset diabetes was found to be more frequent than in the parents of 230 medical students. Assuming a multifactorial poligeneic heredity, the role of common genes predisposing to diabetes cannot be neglected in the manifestation of the two types of the disease. In the families where juvenile diabetes had occurred, the probability of occurrence of juvenile diabetes is considerably higher than that of maturity onset diabetes. This might be in connection with the fact that the provocative factors are different in juvenile and maturity onset diabetes.
在250名糖尿病儿童的父母中,发现青少年期发病型糖尿病和成年期发病型糖尿病的发生率高于230名医科学生的父母。假设存在多因素多基因遗传,那么在这两种类型疾病的表现中,易患糖尿病的共同基因的作用不可忽视。在发生青少年期发病型糖尿病的家庭中,青少年期发病型糖尿病的发生概率显著高于成年期发病型糖尿病。这可能与青少年期发病型糖尿病和成年期发病型糖尿病的诱发因素不同这一事实有关。