Yong W K, Heath D D
Parasite Immunol. 1979 Spring;1(1):27-38. doi: 10.1111/j.1365-3024.1979.tb00693.x.
The 'arc 5' precipitin band, formed when test human serum is reacted against immunoelectophoresed hydatid cyst fluid antigen, has provided a positive diagnosis of Echinococcus granulosus infection. These antibodies to 'arc 5' antigen have now been found in the sera of sheep. They appear 2 weeks after infection with Taenia ovis, after 3 weeks with T. hydatigena and after 16 weeks with E. granulosus. An antigen similar to the 'arc 5' antigen of E. granulosus cyst fluid was also demonstrated in cyst fluid from T. hydatigena, but it would not be positively identified in T. ovis cyst fluid. The presence of 'arc 5' in immunoelectrophoresis tests is not suitable for specific immunodiagnosis of E. granulosus infections in sheep in New Zealand. 'Arc 5' antibodies were only associated with living E. granulosus cysts and were not present if cysts were dead. The location of the cysts in either liver or lungs and the onset of brood capsule production did not influence the presence of 'arc 5' antibodies.
当检测人血清与经免疫电泳的棘球蚴囊液抗原发生反应时形成的“5号弧”沉淀带，已用于确诊细粒棘球绦虫感染。现在发现绵羊血清中存在针对“5号弧”抗原的这些抗体。感染绵羊带绦虫2周后、感染泡状带绦虫3周后以及感染细粒棘球绦虫16周后会出现这些抗体。在泡状带绦虫的囊液中也证实存在一种与细粒棘球绦虫囊液“5号弧”抗原相似的抗原，但在绵羊带绦虫囊液中未得到确切鉴定。免疫电泳试验中“5号弧”的存在不适用于新西兰绵羊细粒棘球绦虫感染的特异性免疫诊断。“5号弧”抗体仅与活的细粒棘球绦虫囊肿相关，囊肿死亡时则不存在。囊肿在肝脏或肺部的位置以及育囊产生的开始时间并不影响“5号弧”抗体的存在。
