[接受定期血液透析的慢性肾功能不全患者的血清补体]
[Serum complement in patients with chronic renal insufficiency undergoing periodic hemodialysis].
作者信息
De Simone C, Perricone R, Taccone Gallucci M, Rovina R, Fontana L, Casciani C U
出版信息
Boll Ist Sieroter Milan. 1979 Jan 31;57(6):757-60.
PMID:552824
Abstract
Assessment of Clq, Cls, C4, C3, C3a, C5, C9, C3PA, C1INH fractions and CH50 activity of serum complement was performed in 24 patients with renal failure undergoing periodic haemodialysis. Alternate pathway activation was found together with high levels of non involved fractions. Mechanisms and biological implications are discussed.
摘要
对24例接受定期血液透析的肾衰竭患者进行了血清补体Clq、Cls、C4、C3、C3a、C5、C9、C3PA、C1INH组分及CH50活性的评估。发现替代途径激活与未参与组分的高水平同时存在。对其机制和生物学意义进行了讨论。
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