Badré R, Guillerm R
Poumon Coeur. 1979;35(6):341-7.
The authors make a brief synthesis of the present data on the penetration and retention of therapeutical aerosols in upper airways. They analyze the mechanisms involved during the penetration of aerosols in the regions of the upper airways which are not swept by the inspiratory airflow, particularly in the accessory cavities of nasal fossa, sinus and Eustachian tube. Experimental results reveal that diffusion of aerosols can be improved at this level either by sound vibrations, or by combining vibrations to intermittent overpressures.
作者对目前有关治疗性气雾剂在上呼吸道的渗透和滞留的数据进行了简要综述。他们分析了气雾剂在未被吸气气流扫过的上呼吸道区域，特别是在鼻窝、鼻窦和咽鼓管的附属腔中的渗透过程中所涉及的机制。实验结果表明，在这个层面上，通过声音振动，或通过将振动与间歇性超压相结合，可以改善气雾剂的扩散。
