Zuber A, Dirnagl K, Drexel H
Med Klin. 1976 Oct 15;71(42):1788-92.
The topical distribution of inhaled aerosols produced by customary jet nebulizers has been measured scintigraphically. Corrections for absorption and stray effects with experimentally determined factors allowed to evaluate the quantities of deposited aerosol for the head, chest and abdominal regions. Highest aerosol intakes were found with slow inhalation through the mouth. The deposition decreased at higher respiration rates with a further diminution when inhalation takes place through the nose. The individuals had characteristic patterns of aerosol distribution resulting in more pronounced deposition differences than those caused by the mode of inhalation.