Cattell W R, Chamberlain D A, Fry I K, McSherry M A, Broughton C, O'Grady F
Br Med J. 1971 Feb 13;1(5745):377-9. doi: 10.1136/bmj.1.5745.377.
Long-term antibacterial therapy with the drug combination trimethoprim-sulphonamide has been used for the treatment of 52 patients with persistent or recurrent bacteriuria. Hypersensitivity or gastrointestinal intolerance was observed in six. Bacteriuria was controlled in 36 out of 38 patients with organisms sensitive to trimethoprim-sulphonamide, 28 having received treatment for periods ranging from 6 to 49 months. Treatment was in some cases curative and in others suppressive or prophylactic. The importance of supportive measures is re-emphasized.
采用甲氧苄啶 - 磺胺药物联合进行长期抗菌治疗，用于治疗52例持续性或复发性菌尿症患者。6例出现过敏反应或胃肠道不耐受。38例对甲氧苄啶 - 磺胺敏感的患者中，36例菌尿得到控制，其中28例接受了6至49个月不等的治疗。治疗在某些情况下具有治愈效果，在其他情况下具有抑制或预防作用。再次强调了支持性措施的重要性。
