Noell W K, Albrecht R
Science. 1971 Apr 2;172(3978):76-9. doi: 10.1126/science.172.3978.76.
Diffuse retinal irradiation by visible light produces in the rat the death of visual cells and pigment epithelium. Typically, cage illumination of 1500 lux from fluorescent light through a green filter leads to severe damage when continued for 40 hours. Vitamin A deficiency protects against this damage but experiments show that retinol released by light from rhodopsin is probably not the toxic agent. Protection against light damage depends on a long-range state of cell adaptation to light itself. The normal diurnal cycle of light and dark seems to be the essential factor in controlling visual cell viability and susceptibility.
可见光对大鼠视网膜的弥漫性照射会导致视觉细胞和色素上皮细胞死亡。通常，通过绿色滤光片的荧光灯产生的1500勒克斯的笼内光照持续40小时会导致严重损伤。维生素A缺乏可预防这种损伤，但实验表明，视紫红质受光释放的视黄醇可能不是有毒物质。对光损伤的防护取决于细胞对光本身的长期适应状态。正常的昼夜明暗循环似乎是控制视觉细胞活力和易感性的关键因素。
