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木糖试验:阿司匹林和吲哚美辛的作用

Xylose test: effect of aspirin and indomethacin.

作者信息

Kendall M J, Nutter S, Hawkins C F

出版信息

Br Med J. 1971 Mar 6;1(5748):533-6. doi: 10.1136/bmj.1.5748.533.

Abstract

The xylose test was used to assess the effect of drugs on intestinal absorption. Both aspirin and indomethacin reduced the urinary output of xylose. By giving xylose intravenously as well as orally it was found that aspirin had a parenteral effect, probably impairing renal function, whereas indomethacin depressed intestinal absorption.

摘要

木糖试验用于评估药物对肠道吸收的影响。阿司匹林和吲哚美辛均降低了木糖的尿排出量。通过静脉注射和口服给予木糖发现,阿司匹林具有肠外效应,可能损害肾功能,而吲哚美辛则抑制肠道吸收。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df44/1795278/a999196be7be/brmedj02249-0032-a.jpg

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