惠普尔病患者十二指肠的内镜表现。

The endoscopic appearance of the duodenum in Whipple's disease.

作者信息

Volpicelli N A, Salyer W R, Milligan F D, Bayless T M, Yardley J H

出版信息

Johns Hopkins Med J. 1976 Jan;138(1):19-23.

Abstract

Duodenoscopic examination of a patient with Whipple's disease revealed that the duodenal mucosa appeared to be partially covered with a yellow-white material. On closer inspection, however, this was found to consist of enlarged villi interspersed with normal-looking mucosa. Histologically these enlarged white villi were shown to contain a heavy accumulation of lipid and typical PAS positive macrophages. The duodenal mucosa was endoscopically normal and histologically showed only a few PAS positive macrophages one year after instituting antibiotic therapy.

摘要

对一名惠普尔病患者进行十二指肠镜检查发现，十二指肠黏膜似乎部分被黄白色物质覆盖。然而，进一步检查发现，这是由肿大的绒毛与外观正常的黏膜相间组成。组织学检查显示，这些肿大的白色绒毛含有大量脂质和典型的PAS阳性巨噬细胞。在开始抗生素治疗一年后，十二指肠黏膜内镜检查正常，组织学检查仅显示少数PAS阳性巨噬细胞。