对乙酰氨基酚与肾损伤。
Paracetamol and renal damage.
作者信息
Edwards O M, Edwards P, Huskisson E C, Taylor R T
出版信息
Br Med J. 1971 Apr 10;2(5753):87-9. doi: 10.1136/bmj.2.5753.87.
Abstract
Renal function was assessed in 18 patients who had consumed 2 to 30 kg of paracetamol. No relationship was found between the total amount of paracetamol taken and any aspect of renal function studied. No patient had clinically significant renal impairment. Thirteen of the patients showed no significant deterioration of renal function over a period of about one year during which they consumed an additional mean 2 kg of paracetamol.
摘要
对18名服用了2至30千克扑热息痛的患者的肾功能进行了评估。未发现扑热息痛的总摄入量与所研究的肾功能的任何方面之间存在关联。没有患者出现具有临床意义的肾功能损害。其中13名患者在大约一年的时间里，肾功能没有明显恶化，在此期间他们平均额外服用了2千克扑热息痛。
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本文引用的文献
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Renal concentrating defect in Sjogren's syndrome.干燥综合征中的肾浓缩功能缺陷。
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Paracetamol and the kidney.对乙酰氨基酚与肾脏
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Papillary necrosis in experimental analgesic nephropathy.实验性镇痛剂肾病中的乳头坏死
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Papillary necrosis in rats caused by aspirin and aspirin-containing mixtures.阿司匹林及含阿司匹林混合物所致大鼠乳头坏死
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