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血吸虫病母婴免疫变化的初步报告。I. 免疫球蛋白变化。

A preliminary report on the materno-foetal immunological changes in schistosomiasis. I. Immunoglobulin changes.

作者信息

Abbassy A F, Shaker Z A, el-Raziky E H, Aboul-Ezz F M, Naguib Y A

出版信息

Egypt J Bilharz. 1978;5(1-2):71-6.

PMID:555756
Abstract

Twenty five simple bilharzial pregnant females together with eight control non-bilharzial gravid women were included in this study. Quantitation of immunoglobulins G and M was performed on both maternal and cord blood sera. The transmission of IgG through the placenta was suggested by the trend for positive correlation between foetal and maternal IgG levels. Maternal IgG was significantly higher in the active bilharzial group compared with the non-active group. Foetal IgM was significantly higher in the active bilharzial group compared with the control non-bilharzial cases.

摘要

本研究纳入了25名单纯血吸虫病孕妇以及8名对照非血吸虫病孕妇。对母血和脐血血清进行了免疫球蛋白G和M的定量检测。胎儿和母体IgG水平呈正相关趋势,提示IgG可通过胎盘传递。与非活动期组相比,活动期血吸虫病组母体IgG显著更高。与对照非血吸虫病病例相比,活动期血吸虫病组胎儿IgM显著更高。

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