el-Raziky E H, Shaker Z A, Abbassy A F, Aboul-Ezz F M, Naguib Y A
Egypt J Bilharz. 1978;5(1-2):77-84.
Twenty five pregnant simple bilharzial patients together with 8 non-bilharzial pregnant women and 14 bilharzial non-pregnant females were included in this study. Circulating bilharzial antigens were tested in all groups by the IHA technique. Both IHA and COP were used for detection of bilharzial antibodies in the same groups. Bilharzial antigenaemia was higher in pregnant bilharzial women than in non-pregnant ones. The bilharzial antibodies were detectable in a smaller percentage of bilharzial pregnant women than in non-pregnant ones. Also, the IHA antibody titers and COP grades were lower in the former than in the latter; a total picture suggestive of depressed humoral immune response in pregnant bilharzial women. The passage of circulating bilharzial antigens and antibodies through the placenta to the foetus is demonstrated.
本研究纳入了25名单纯血吸虫病孕妇、8名非血吸虫病孕妇以及14名非妊娠血吸虫病女性。采用间接血凝试验（IHA）技术检测了所有组的循环血吸虫抗原。在同一组中同时使用IHA和环卵沉淀试验（COP）检测血吸虫抗体。血吸虫病孕妇的血吸虫抗原血症高于非孕妇。与非孕妇相比，血吸虫病孕妇中可检测到血吸虫抗体的比例较小。此外，前者的IHA抗体滴度和COP分级低于后者；总体情况表明血吸虫病孕妇的体液免疫反应受到抑制。研究证实了循环血吸虫抗原和抗体可通过胎盘传递给胎儿。
