Black R B, Roberts G, Rhodes J
Gut. 1971 Jul;12(7):552-8. doi: 10.1136/gut.12.7.552.
Bile reflux has been studied by serial estimations of bile acid concentrations in the stomach before and after a liquid meal. Thirteen normal subjects and 38 patients with gastric ulcer were examined. Thirty-one in the ulcer group had the test repeated once or twice within two months of the initial test to observe any change in reflux associated with healing. Patients with gastric ulcer had significantly higher concentrations of bile acids than normal subjects, both before and after the meal, although there was an overlap between the groups. In patients with an ulcer which healed or showed some healing over two months, no consistent change in reflux was found.
通过对流食前后胃内胆汁酸浓度进行系列测定来研究胆汁反流情况。对13名正常受试者和38名胃溃疡患者进行了检查。溃疡组中有31人在初次检查后的两个月内重复进行了一到两次该测试,以观察与愈合相关的反流变化。胃溃疡患者在进食前后的胆汁酸浓度均显著高于正常受试者,尽管两组之间存在重叠。在溃疡在两个月内愈合或显示出一定愈合迹象的患者中,未发现反流有一致的变化。