单胺氧化酶抑制剂预处理家兔后吗啡、哌替啶和喷他佐辛效果的比较
Comparison of the effects of morphine, pethidine and pentazocine in rabbits pretreated with a monoamine oxidase inhibitor.
作者信息
Penn R G, Rogers K J
出版信息
Br J Pharmacol. 1971 Jul;42(3):485-92. doi: 10.1111/j.1476-5381.1971.tb07133.x.
Abstract
- Rabbits were premedicated with pargyline and the changes in rectal temperature measured after the intravenous infusion of morphine, pentazocine and pethidine.2. Pethidine produced pronounced rises in rectal temperature which were dose dependent. One out of the four rabbits given 1 mg/kg died in hyperthermia. Four out of the four rabbits given 5 mg/kg died in hyperthermia. Doses of 10 mg/kg of pethidine caused no significant change in the rectal temperature of rabbits not pretreated with pargyline.3. Morphine and pentazocine in doses of 1 mg and 10 mg/kg did not significantly alter the rectal temperature of rabbits pretreated with pargyline except for one rabbit which developed a delayed hyperthermia following the injection of morphine 1 mg/kg.
摘要
给兔子预先用优降宁进行预处理，然后在静脉注射吗啡、喷他佐辛和哌替啶后测量直肠温度的变化。
哌替啶可使直肠温度显著升高，且呈剂量依赖性。给予1mg/kg的四只兔子中有一只死于体温过高。给予5mg/kg的四只兔子全部死于体温过高。给予10mg/kg哌替啶时，未用优降宁预处理的兔子直肠温度无显著变化。
1mg和10mg/kg剂量的吗啡和喷他佐辛对用优降宁预处理的兔子的直肠温度无显著影响，但有一只兔子在注射1mg/kg吗啡后出现延迟性体温过高。
相似文献
1
Comparison of the effects of morphine, pethidine and pentazocine in rabbits pretreated with a monoamine oxidase inhibitor.单胺氧化酶抑制剂预处理家兔后吗啡、哌替啶和喷他佐辛效果的比较
Br J Pharmacol. 1971 Jul;42(3):485-92. doi: 10.1111/j.1476-5381.1971.tb07133.x.
2
The role of 5-hydroxytryptamine and noradrenaline in the hyperthermic reaction induced by pethidine in rabbits pretreated with pargyline.5-羟色胺和去甲肾上腺素在帕吉林预处理的家兔中由哌替啶诱发的体温过高反应中的作用
Br J Pharmacol. 1972 Nov;46(3):416-22. doi: 10.1111/j.1476-5381.1972.tb08139.x.
3
Role of brain monoamines in the fatal hyperthermia induced by pethidine or imipramine in rabbits pretreated with a monoamine oxidase inhibitor.脑单胺在单胺氧化酶抑制剂预处理的家兔中，由哌替啶或丙咪嗪诱发的致死性体温过高里的作用
Br J Pharmacol. 1973 May;48(1):12-8. doi: 10.1111/j.1476-5381.1973.tb08217.x.
4
5
Actions of morphine, pethidine and pentazocine on the oestrus and pregnant rat uterus in vitro.
Br J Anaesth. 1985 Apr;57(4):430-3. doi: 10.1093/bja/57.4.430.
6
A cross-over comparison of the effect of morphine, pethidine, pentazocine, and phenazocine on biliary pressure.吗啡、哌替啶、喷他佐辛和非那佐辛对胆道压力影响的交叉对照比较。
Gut. 1971 Mar;12(3):218-21. doi: 10.1136/gut.12.3.218.
7
Modification by monoamine oxidase inhibitors of the analgesic, hypothermic and toxic actions of morphine and pethidine in mice.单胺氧化酶抑制剂对小鼠体内吗啡和哌替啶的镇痛、降温及毒性作用的修饰。
J Pharm Pharmacol. 1978 Jan;30(1):36-40. doi: 10.1111/j.2042-7158.1978.tb13149.x.
8
Role of 5-hydroxytryptamine in morphine-, pethidine-, and methadone-induced hypothermia in rats at low ambient and room temperature.5-羟色胺在低环境温度和室温下对大鼠吗啡、哌替啶和美沙酮诱导的体温过低中的作用。
Br J Pharmacol. 1977 Jul;60(3):323-30. doi: 10.1111/j.1476-5381.1977.tb07503.x.
9
Interaction of butorphanol, with monoamine oxidase inhibitor, tranylcypromine.布托啡诺与单胺氧化酶抑制剂反苯环丙胺的相互作用。
Forensic Sci Int. 1991 Mar;49(2):185-92. doi: 10.1016/0379-0738(91)90078-w.
10
Mechanism of hyperthermia in the interaction between pethidine or imipramine and monoamine oxidase inhibitors.
Med J Malaysia. 1973 Jun;27(4):280-3.
引用本文的文献
1
The serotonin syndrome. Implicated drugs, pathophysiology and management.血清素综合征。相关药物、病理生理学及管理。
Drug Saf. 1995 Aug;13(2):94-104. doi: 10.2165/00002018-199513020-00004.
2
Effect of nonselective and selective inhibitors of monoamine oxidases A and B on pethidine toxicity in mice.单胺氧化酶A和B的非选择性及选择性抑制剂对小鼠哌替啶毒性的影响。
Br J Pharmacol. 1984 May;82(1):151-4. doi: 10.1111/j.1476-5381.1984.tb16452.x.
3
Pentazocine: a review of its pharmacological properties, therapeutic efficacy and dependence liability.喷他佐辛：其药理特性、治疗效果及成瘾倾向综述
Drugs. 1973;5(1):6-91. doi: 10.2165/00003495-197305010-00002.
4
Compulsive gnawing in rats after implantation of drugs into the ventral thalamus. A contribution to the mechanism of morphine action.将药物植入大鼠腹侧丘脑后大鼠的强迫性啃咬行为。对吗啡作用机制的一种探讨。
Br J Pharmacol. 1974 Jun;51(2):197-205. doi: 10.1111/j.1476-5381.1974.tb09647.x.
5
Role of brain monoamines in the fatal hyperthermia induced by pethidine or imipramine in rabbits pretreated with a monoamine oxidase inhibitor.脑单胺在单胺氧化酶抑制剂预处理的家兔中，由哌替啶或丙咪嗪诱发的致死性体温过高里的作用
Br J Pharmacol. 1973 May;48(1):12-8. doi: 10.1111/j.1476-5381.1973.tb08217.x.
6
The role of 5-hydroxytryptamine and noradrenaline in the hyperthermic reaction induced by pethidine in rabbits pretreated with pargyline.5-羟色胺和去甲肾上腺素在帕吉林预处理的家兔中由哌替啶诱发的体温过高反应中的作用
Br J Pharmacol. 1972 Nov;46(3):416-22. doi: 10.1111/j.1476-5381.1972.tb08139.x.
7
Monoamine oxidase inhibitors revisited.再谈单胺氧化酶抑制剂。
Can J Anaesth. 1989 Jan;36(1):64-74. doi: 10.1007/BF03010890.
8
MAOIs to RIMAs in anaesthesia--a literature review.麻醉中从单胺氧化酶抑制剂到可逆性单胺氧化酶抑制剂——一篇文献综述
Psychopharmacology (Berl). 1992;106 Suppl:S43-5. doi: 10.1007/BF02246234.
9
MAO inhibitors and coronary artery surgery: a patient death.
Can J Anaesth. 1992 Dec;39(10):1061-6. doi: 10.1007/BF03008376.
10
Furazolidone-pethidine interaction in rabbits.呋喃唑酮与哌替啶在兔体内的相互作用。
Br J Pharmacol. 1975 Dec;55(4):497-501. doi: 10.1111/j.1476-5381.1975.tb07424.x.
本文引用的文献
1
Dangerous potentiation of pethidine by iproniazid, and its treatment.异烟肼对哌替啶的危险增效作用及其治疗
Br Med J. 1960 Aug 13;2(5197):507-9. doi: 10.1136/bmj.2.5197.507.
2
Fatal toxic encephalitis occurring during iproniazid therapy in pulmonary tuberculosis.肺结核患者接受异烟肼治疗期间发生的致命性中毒性脑炎。
Ann Intern Med. 1955 Feb;42(2):417-24. doi: 10.7326/0003-4819-42-2-417.
3
EFFECTS ON TEMPERATURE OF AMINES INJECTED INTO THE CEREBRAL VENTRICLES. A NEW CONCEPT OF TEMPERATURE REGULATION.注入脑室的胺类对体温的影响。体温调节的新概念。
J Physiol. 1964 Sep;173(2):226-31. doi: 10.1113/jphysiol.1964.sp007454.
4
MONOAMINE OXIDASE INHIBITORS. ADVERSE REACTIONS AND POSSIBLE MECHANISMS.单胺氧化酶抑制剂。不良反应及可能机制。
JAMA. 1964 Nov 2;190:456-62.
5
REACTIONS DUE TO THE COMBINATION OF MONOAMINEOXIDASE INHIBITORS WITH THYMOLEPTICS, PETHIDINE, OR METHYLAMPHETAMINE.单胺氧化酶抑制剂与抗抑郁药、哌替啶或甲基苯丙胺联合使用引起的反应。
Lancet. 1963 Sep 7;2(7306):524-5. doi: 10.1016/s0140-6736(63)90265-4.
6
Potentiation of amphetamine and pethidine by monoamineoxidase inhibitors.单胺氧化酶抑制剂对苯丙胺和哌替啶的增效作用。
Lancet. 1963 Mar 23;1(7282):669. doi: 10.1016/s0140-6736(63)91307-2.
7
The pyretogenic effect of 5-hydroxytryptophan and its comparison with that of ISD.5-羟色氨酸的致热作用及其与异烟肼的比较。
J Pharmacol Exp Ther. 1958 Feb;122(2):195-200.
8
Pethidine and liver damage.哌替啶与肝损伤
Br Med J. 1952 Sep 27;2(4786):703-4. doi: 10.1136/bmj.2.4786.703.
9
Inhibition of endotoxin fever by reserpine.利血平对内毒素发热的抑制作用。
Proc Soc Exp Biol Med. 1966 Jul;122(3):746-9. doi: 10.3181/00379727-122-31242.
10
The interaction between monoamine oxidase inhibitors and narcotic analgesics in mice.小鼠体内单胺氧化酶抑制剂与麻醉性镇痛药之间的相互作用。
Br J Pharmacol. 1969 Jul;36(3):470-80. doi: 10.1111/j.1476-5381.1969.tb08003.x.
Zotero 插件