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酵母中的微小突变。II. 含有较小线粒体脱氧核糖核酸的突变体的分离。

Petite mutation in yeast. II. Isolation of mutants containing mitochondrial deoxyribonucleic acid of reduced size.

作者信息

Goldring E S, Grossman L I, Marmur J

出版信息

J Bacteriol. 1971 Jul;107(1):377-81. doi: 10.1128/jb.107.1.377-381.1971.

DOI:10.1128/jb.107.1.377-381.1971
PMID:5563875
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC246929/
Abstract

A series of petite mutants of Saccharomyces cerevisiae, generated after treatment for various times with ethidium bromide, was isolated, and the mitochondrial deoxyribonucleic acid size for each member was estimated. It was found that, as the treatment time with ethidium bromide was increased, the mitochondrial deoxyribonucleic acid isolated from the petite series was increasingly reduced in size.

摘要

分离出一系列经溴化乙锭处理不同时间后产生的酿酒酵母小菌落突变体，并估算了每个突变体的线粒体脱氧核糖核酸大小。结果发现，随着溴化乙锭处理时间的增加，从小菌落系列中分离出的线粒体脱氧核糖核酸大小越来越小。

相似文献

1
Petite mutation in yeast. II. Isolation of mutants containing mitochondrial deoxyribonucleic acid of reduced size.酵母中的微小突变。II. 含有较小线粒体脱氧核糖核酸的突变体的分离。
J Bacteriol. 1971 Jul;107(1):377-81. doi: 10.1128/jb.107.1.377-381.1971.
2
Control of the mitochondrial genome in Saccharomyces cerevisiae. The fate of mitochondrial membrane proteins and mitochondrial deoxyribonucleic acid during petite induction.酿酒酵母中线粒体基因组的控制。小菌落诱导过程中线粒体膜蛋白和线粒体脱氧核糖核酸的命运。
J Biol Chem. 1971 Aug 25;246(16):5113-9.
3
Mitochondrial DNA from cytoplasmic petite mutants of yeast.来自酵母细胞质小菌落突变体的线粒体DNA。
Biochim Biophys Acta. 1972 Aug 16;277(1):35-43. doi: 10.1016/0005-2787(72)90349-8.
4
Mitochondrial DNA deficient petite mutants of yeast.酵母的线粒体DNA缺陷型小菌落突变体。
Biochem Biophys Res Commun. 1970 Jun 5;39(5):989-96. doi: 10.1016/0006-291x(70)90422-5.
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The petite mutation in yeast. Loss of mitochondrial deoxyribonucleic acid during induction of petites with ethidium bromide.酵母中的小菌落突变。用溴化乙锭诱导小菌落时线粒体脱氧核糖核酸的丢失。
J Mol Biol. 1970 Sep 14;52(2):323-35. doi: 10.1016/0022-2836(70)90033-1.
6
Molecular consequences of ethidium bromide mutagenesis.溴化乙锭诱变的分子后果。
Nat New Biol. 1971 May 5;231(18):12-6.
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The unusual properties of mtDNA from a "low-density" petite mutant of yeast.酵母“低密度”小菌落突变体线粒体DNA的异常特性。
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DNA-DNA hybridization studies of mitochondrial DNA of ethidium-bromide-induced petite mutants of yeast.溴化乙锭诱导的酵母小菌落突变体线粒体DNA的DNA-DNA杂交研究
Eur J Biochem. 1974 Feb 15;42(1):67-71. doi: 10.1111/j.1432-1033.1974.tb03315.x.
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Mitochondrial DNA and suppressiveness of petite mutants in Saccharomyces cerevisiae.线粒体DNA与酿酒酵母中小菌落突变体的抑制性
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Isolation of circular DNA from a mitochondrial fraction from yeast.从酵母线粒体组分中分离环状DNA。
Proc Natl Acad Sci U S A. 1972 Feb;69(2):388-92. doi: 10.1073/pnas.69.2.388.

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本文引用的文献

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SEDIMENTATION STUDIES OF THE SIZE AND SHAPE OF DNA.DNA大小与形状的沉降研究
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Tetrazolium overlay technique for population studies of respiration deficiency in yeast.用于酵母呼吸缺陷群体研究的四氮唑覆盖技术
Science. 1957 May 10;125(3254):928-9. doi: 10.1126/science.125.3254.928.
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Mitochondrial DNA from yeast "petite" mutants: specific changes in buoyant density corresponding to different cytoplasmic mutations.酵母“小菌落”突变体的线粒体DNA：对应不同细胞质突变的浮力密度的特定变化。
Biochem Biophys Res Commun. 1966 Jul 20;24(2):218-24. doi: 10.1016/0006-291x(66)90723-6.
4
Cytoplasmic DNA from petite colonies of Saccharomyces cerevisiae: a hypothesis on the nature of the mutation.来自酿酒酵母小菌落的细胞质DNA：关于突变本质的一种假说。
Science. 1969 Mar 21;163(3873):1331-3. doi: 10.1126/science.163.3873.1331.
5
Ethidium bromide induced mutation of yeast mitochondria: complete transformation of cells into respiratory deficient non-chromosomal "petites".溴化乙锭诱导酵母线粒体突变：细胞完全转变为呼吸缺陷型非染色体“小菌落”。
Biochem Biophys Res Commun. 1968 Feb 15;30(3):232-9. doi: 10.1016/0006-291x(68)90440-3.
6
The petite mutation in yeast. Loss of mitochondrial deoxyribonucleic acid during induction of petites with ethidium bromide.酵母中的小菌落突变。用溴化乙锭诱导小菌落时线粒体脱氧核糖核酸的丢失。
J Mol Biol. 1970 Sep 14;52(2):323-35. doi: 10.1016/0022-2836(70)90033-1.
7
Mitochondrial DNA deficient petite mutants of yeast.酵母的线粒体DNA缺陷型小菌落突变体。
Biochem Biophys Res Commun. 1970 Jun 5;39(5):989-96. doi: 10.1016/0006-291x(70)90422-5.
8
Preferential synthesis of yeast mitochondrial DNA in the absence of protein synthesis.在缺乏蛋白质合成的情况下酵母线粒体DNA的优先合成。
J Mol Biol. 1969 Dec 28;46(3):367-76. doi: 10.1016/0022-2836(69)90182-x.