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姿势、瓦尔萨尔瓦动作及咳嗽对肝硬化门静脉高压的影响

The influence of posture, Valsalva manoeuvre and coughing on portal hypertension in cirrhosis.

作者信息

Burcharth F, Bertheussen K

出版信息

Scand J Clin Lab Invest. 1979 Nov;39(7):665-9. doi: 10.1080/00365517909108872.

DOI:10.1080/00365517909108872
PMID:556537
Abstract

Percutaneous transhepatic catheterization of the portal venous system and pressure readings were performed in nineteen patients with cirrhosis of the liver and bleeding varices. Portal pressures were recorded in awake and mobile patients in supine, sitting and standing position, during sleep, ingestion of food, Valsalva manoeuvre and coughing. No significant differences were recorded in the different postures, during sleep or food intake. Four patients with hepatofugal portal blood flow had, however, lowest pressure in standing position. During Valsalva manoeuvre portal pressure was doubled, and it became fourfold during coughing. Elevations of this magnitude have not previously been reported. A relationship was found between portal pressure and size of varices.

摘要

对19例肝硬化伴静脉曲张出血患者进行了经皮肝门静脉系统插管及压力测量。在清醒且可活动的患者中,于仰卧位、坐位和站立位、睡眠期间、进食时、瓦尔萨尔瓦动作及咳嗽时记录门静脉压力。在不同体位、睡眠或进食期间未记录到显著差异。然而,4例存在肝外门静脉血流的患者在站立位时压力最低。在瓦尔萨尔瓦动作期间门静脉压力加倍,咳嗽时变为四倍。此前尚未报道过如此大幅度的升高。发现门静脉压力与静脉曲张大小之间存在关联。

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