Zacchetti O, Di Giovanni T, Gemignani F, Mancia D, Terzano M G
Ateneo Parmense Acta Biomed. 1977;48(3):243-57.
The authors take into consideration the reactivity of the E.E. Graphic focal anomalies to the i.v. infusion of 10 mg Diazepam. The cases includ 28 patients (15 with cerebral neoplasia, 8 with severe vascular accident, 5 with light vascular accident); among these, 19 showed typical E.E. Graphic focuses after administration of Diapezam, like those previously described by Weber and other Authors. Subjects with severe cerebral lesions and in the third age, after i.v. administration of 10 mg Diazepam showed vegetative disorders (hypotension, tachycardia or bradycardia, apnoea, periodic respiration). The reliability of the reactivity of the EEG focal anomalies to i.v. administration of Diazepam is confuted and the risks of such a methodology in subjects with severe cerebral damage or in the third age, are pointed out.
作者们考虑了脑电图图形局灶性异常对静脉注射10毫克地西泮的反应性。病例包括28名患者（15例患有脑肿瘤，8例患有严重血管意外，5例患有轻度血管意外）；其中，19例在给予地西泮后出现典型的脑电图图形病灶，如同先前韦伯和其他作者所描述的那样。患有严重脑损伤的老年受试者在静脉注射10毫克地西泮后出现植物神经功能紊乱（低血压、心动过速或心动过缓、呼吸暂停、周期性呼吸）。脑电图局灶性异常对静脉注射地西泮反应性的可靠性遭到驳斥，并指出了这种方法在患有严重脑损伤的受试者或老年受试者中的风险。
