脂质探针和标记蛋白在细胞膜上的侧向转运。
Lateral transport of a lipid probe and labeled proteins on a cell membrane.
作者信息
Schlessinger J, Axelrod D, Koppel D E, Webb W W, Elson E L
出版信息
Science. 1977 Jan 21;195(4275):307-9. doi: 10.1126/science.556653.
PMID:556653
Abstract
Diffusion coefficients (D) of a lipid probe and labeled proteins on L-6 myoblast membranes have been measured giving D(protein) approximately 2 X 10(-10) square centimeter per second and D (lipid probe) approximately 9 X 10(-9) square centimeter per second. Some of the membrane proteins are immobile, but the lipid probe diffuses freely over macroscopic distances. Cytochalasin B slows protein but not lipid probe diffusion.
摘要
已测量了脂质探针和标记蛋白在L-6成肌细胞膜上的扩散系数（D），得出D（蛋白）约为2×10⁻¹⁰平方厘米每秒，D（脂质探针）约为9×10⁻⁹平方厘米每秒。一些膜蛋白是不移动的，但脂质探针能在宏观距离上自由扩散。细胞松弛素B会减缓蛋白扩散，但不影响脂质探针的扩散。
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