平面脂质双分子层中的横向扩散。
Lateral diffusion in planar lipid bilayers.
作者信息
Fahey P F, Koppel D E, Barak L S, Wolf D E, Elson E L, Webb W W
出版信息
Science. 1977 Jan 21;195(4275):305-6. doi: 10.1126/science.831279.
PMID:831279
Abstract
Direct measurements by fluorescence correlation spectroscopy of lateral diffusion coefficients of fluorescent lipid analogs in lipid bilaryer membranes indicate self-diffusion coefficients D greater than 10(-7) square centimeters per second for various lipid systems above their reported transition temperatures. Cholesterol in egg lecithin at mole ratio of 1 : 2 reduces D by about twofold, while retained hydrocarbon solvent can increase it by two- to threefold.
摘要
通过荧光相关光谱法直接测量脂质双分子层膜中荧光脂质类似物的横向扩散系数，结果表明，在高于其报道的转变温度时，各种脂质体系的自扩散系数D大于10^(-7)平方厘米每秒。摩尔比为1:2的卵磷脂中的胆固醇使D降低约两倍，而残留的烃类溶剂可使其增加两到三倍。
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