Martin S W
Can J Comp Med. 1977 Jan;41(1):19-25.
In order to correctly evaluate a test, at least four attributes should be measured: namely, sensitivity, specificity, accuracy and precision. Sensitivity is the proportion of diseased animals which are correctly identified, whereas specificity is the proportion of healthy animals which are correctly identified. These two attributes are important, not only because of the reasons implied by their definition but because they influence both the apparent prevalence of disease and proportion of test-positive animals which are actually diseased. The ability of a test to give a true measurement of the substance being measured, its accuracy, and its ability to give consistent results on the same sample, its precision, are good measures of quality control. Both these attributes influence the sensitivity and specificity of the test. Inaccuracies and inconsistencies arise from the test itself, the technician and the nature of the sample being tested.
为了正确评估一项检测,至少应测量四个属性:即灵敏度、特异性、准确性和精密度。灵敏度是被正确识别的患病动物的比例,而特异性是被正确识别的健康动物的比例。这两个属性很重要,不仅因为其定义所隐含的原因,还因为它们会影响疾病的表观患病率以及检测呈阳性的动物中实际患病的比例。一项检测给出所测物质真实测量值的能力(即其准确性)以及对同一样本给出一致结果的能力(即其精密度),是质量控制的良好指标。这两个属性都会影响检测的灵敏度和特异性。不准确和不一致的情况源于检测本身、技术人员以及被检测样本的性质。