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口服色甘酸二钠治疗溃疡性结肠炎。一项双盲对照试验。

Treatment of ulcerative colitis with oral disodium cromoglycate. A double-blind controlled trial.

作者信息

Mani V, Lloyd G, Green F H, Fox H, Turnberg L A

出版信息

Lancet. 1976 Feb 28;1(7957):439-41. doi: 10.1016/s0140-6736(76)91471-9.

Abstract

Twelve patients with ulcerative protocolitis were treated for six months with each of oral disodium cromoglycate (2 g/day) and placebo in a double-blind cross-over trial. The active drug significantly improved the patients' sense of well-being and the signoidoscopic and rectal biopsy appearances. Orally administered disodium cromoglycate may have a place in the long-term management of colitis.

摘要

在一项双盲交叉试验中,12名溃疡性直肠炎患者分别接受口服色甘酸二钠(2克/天)和安慰剂治疗,为期6个月。活性药物显著改善了患者的幸福感以及乙状结肠镜和直肠活检的表现。口服色甘酸二钠可能在结肠炎的长期管理中占有一席之地。

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