溃疡性结肠炎中的食物过敏与特异性IgE

Dietary allergy and specific IgE in ulcerative colitis.

作者信息

Jones D B, Kerr G D, Parker J H, Wilson R S

出版信息

J R Soc Med. 1981 Apr;74(4):292-3. doi: 10.1177/014107688107400411.

DOI:10.1177/014107688107400411

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1438360/

Abstract

Previous authors have considered that allergy to certain foodstuffs may play an important role in the aetiology of ulcerative colitis, but immunological evidence for dietary allergy in ulcerative colitis is inconclusive. A study is reported of 22 patients with ulcerative colitis, with matched controls, in whom total serum IgE and specific IgE to certain foodstuffs have been estimated by the Phadebas PRIST and RAST (Pharmacia) techniques. Allergens tested were egg-white, milk, wheat, rye, oat, fish (cod) and peanut. There was no significant difference in the total serum IgE levels and the food specific IgE activity between the two groups.

摘要

以往的作者认为，对某些食物的过敏可能在溃疡性结肠炎的病因学中起重要作用，但溃疡性结肠炎饮食过敏的免疫学证据尚无定论。本文报道了一项对22例溃疡性结肠炎患者及匹配对照组的研究，通过Phadebas PRIST和RAST（Pharmacia）技术对血清总IgE及对某些食物的特异性IgE进行了测定。检测的变应原包括蛋清、牛奶、小麦、黑麦、燕麦、鱼（鳕鱼）和花生。两组之间血清总IgE水平及食物特异性IgE活性无显著差异。

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本文引用的文献

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A CONTROLLED THERAPEUTIC TRIAL OF VARIOUS DIETS IN ULCERATIVE COLITIS.溃疡性结肠炎不同饮食的对照治疗试验

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Lancet. 1967 Nov 25;2(7526):1105-7. doi: 10.1016/s0140-6736(67)90615-0.

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