人子宫酶从催产素中释放出亮氨酰甘氨酰胺。
Leucylglycinamide released from oxytocin by human uterine enzyme.
作者信息
Walter R, Shlank H, Glass J D, Schwartz I L, Kerenyi T D
出版信息
Science. 1971 Aug 27;173(3999):827-9. doi: 10.1126/science.173.3999.827.
PMID:5572174
Abstract
Uteri of pregnant and nonpregnant women contain enzymic activities which inactivate oxytocin. A potent enzyme, which has been partially purified from uterine homogenates, cleaves the prolyl-leucyl peptide bond of oxytocin. This findinig associates for the first time the release of the dipeptide leucylglycinamide with the degradation of neurohypophyseal hormones.
摘要
孕妇和非孕妇的子宫均含有使催产素失活的酶活性。一种已从子宫匀浆中部分纯化的强效酶，可裂解催产素的脯氨酰 - 亮氨酰肽键。这一发现首次将二肽亮氨酰甘氨酰胺的释放与神经垂体激素的降解联系起来。
Zotero 插件