苯酚暴露评估：苯酚蒸气在肺部的吸收、经皮肤的吸收以及苯酚在尿液中的排泄。
Evaluation of exposure to phenol: absorption of phenol vapour in the lungs and through the skin and excretion of phenol in urine.
作者信息
Piotrowski J K
出版信息
Br J Ind Med. 1971 Apr;28(2):172-8. doi: 10.1136/oem.28.2.172.
Abstract
172-178. Volunteers were exposed to phenol vapour (5 to 25 mg/m) by inhalation and through the skin, respectively, and the excretion of phenol in urine was examined. The retention of vapour in the lungs decreased from about 80 to 70% in the course of exposure. The absorption of vapour through the whole of the skin was approximately proportional to the concentration of vapour used, the absorption rate being somewhat lower than in the lungs. Almost 100% of the phenol was excreted in the urine within one day. The rate of excretion of phenol in the urine may be used as an exposure test which permits the absorbed dose to be estimated with a precision of about ±2 mg.
摘要
172 - 178. 志愿者分别通过吸入和皮肤接触苯酚蒸气（5至25毫克/立方米），并检测尿中苯酚的排泄情况。在接触过程中，肺部蒸气潴留率从约80%降至70%。经整个皮肤吸收的蒸气量大致与所用蒸气浓度成正比，吸收速率略低于肺部。几乎100%的苯酚在一天内随尿液排出。尿中苯酚的排泄率可用作暴露试验，据此可精确估计吸收剂量，精度约为±2毫克。
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