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新生大脑中的DNA(细胞数量):母体(F0)饮食蛋白质限制导致的第二代(F2)改变。

DNA (cell number) in neonatal brain: second generation (F2) alteration by maternal (F0) dietary protein restriction.

作者信息

Zamenhof S, van Marthens E, Grauel L

出版信息

Science. 1971 May 21;172(3985):850-1. doi: 10.1126/science.172.3985.850.

Abstract

Female rats were maintained on a protein-restricted diet 1 month prior to mating and throughout pregnancy. Their female offspring were maintained on a normal diet from birth or from weaning and were mated with normal males. The second generation offspring at birth still had significantly lower cerebral weight and total cerebral DNA (cerebral cell number).

摘要

雌性大鼠在交配前1个月及整个孕期维持蛋白质限制饮食。它们的雌性后代从出生或断奶后开始维持正常饮食,并与正常雄性大鼠交配。第二代后代出生时脑重量和脑总DNA(脑细胞数量)仍显著较低。

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