Nubar Y
Biophys J. 1971 Mar;11(3):252-64. doi: 10.1016/S0006-3495(71)86212-4.
The viscosity of blood, measured by the usual viscometers in which slip is not considered, is found to be flow dependent, varying markedly with shear rate, pressure gradient, and vessel diameter in the lower ranges of these factors. The study postulates, on grounds thought reasonable, that slip may be present in blood flow, as a function of the nature of the wall surfaces, shear stress at the wall, and relative cell volume (RCV) adjacent to the wall. It presumes that blood possesses a specific, flow-independent viscosity, and determines theoretically the viscosity indications of viscometers if blood slipped in the instruments. The study shows that if the slip function is of a certain plausible form, these viscosity indications would exhibit a flow dependence of much the same pattern as the actual indications supplied by the usual viscometers. The slip postulate permits, therefore, an interpretation of the "anomalous" flow behavior of blood, dispensing with the prevailing assumption of an ad hoc variability of its viscosity with flow factors. To the extent that viscometric data for blood may be representative of other non-newtonian fluids, the slip postulate may be applicable to these fluids.
用通常不考虑滑移的粘度计测量血液粘度时，发现其与流动有关，在这些因素的较低范围内，会随剪切速率、压力梯度和血管直径显著变化。该研究基于合理的理由假定，血流中可能存在滑移，这是壁面性质、壁面剪切应力以及壁面附近相对细胞体积（RCV）的函数。它假定血液具有特定的、与流动无关的粘度，并从理论上确定了如果血液在仪器中发生滑移时粘度计的粘度指示。研究表明，如果滑移函数具有某种合理的形式，这些粘度指示将呈现出与通常粘度计提供的实际指示非常相似的流动依赖性。因此，滑移假设允许对血液的“异常”流动行为进行解释，摒弃了其粘度随流动因素特别变化的普遍假设。就血液的粘度测量数据可能代表其他非牛顿流体而言，滑移假设可能适用于这些流体。
