Taylor K M, Snyder S H
Science. 1971 Jun 4;172(3987):1037-9. doi: 10.1126/science.172.3987.1037.
Histamine content of rat brain was lowered quickly by inhibitors of histidine decarboxylase, suggesting that a portion of brain histamine turns over rapidly. Restraint and exposure to cold also reduced brain histamine levels and markedly augmented its formation in the hypothalamus.
组氨酸脱羧酶抑制剂可迅速降低大鼠脑内组胺含量,这表明脑内一部分组胺更新很快。束缚和寒冷暴露也会降低脑内组胺水平,并显著增加其在下丘脑中的生成。