海蒽酮：一种移码诱变剂。
Hycanthone: a frameshift mutagen.
作者信息
Hartman P E, Levine K, Hartman Z, Berger H
出版信息
Science. 1971 Jun 4;172(3987):1058-60. doi: 10.1126/science.172.3987.1058.
PMID:5573958
Abstract
Rapid spot-test screening of antischistosomal agents reveals that hycanthone is a potent frameshift mutagen while the closely related compound, miracil D, is nonmutagenic in Salmonella. Both hycanthone and miracil D are frameshift mutagens for T4 bacteriophage during growth in Escherichia coli.
摘要
抗血吸虫药的快速斑点试验筛选表明，海恩酮是一种强效的移码诱变剂，而与之密切相关的化合物米拉西啶D在沙门氏菌中无诱变作用。在大肠杆菌中生长期间，海恩酮和米拉西啶D对T4噬菌体均为移码诱变剂。
Zotero 插件