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显性和环境方差:它们对根据双胞胎数据估计的遗传力的影响。

Dominance and environmental variances: their effect on heritabilities estimated from twin data.

作者信息

Kang K W, Corey L A, Evans M M, Christian J C, Norton J A

出版信息

Hum Hered. 1977;27(1):9-21. doi: 10.1159/000152848.

Abstract

A method for partitioning genetic variance estimated from twin data into additive and dominance variances was presented using Falconer's variance component model. The effects of dominance and environmental variances on a number of heritability estimates were also reviewed. A heritability estimate, based on the analysis of variance and the genetic variance estimates presented by HASEMAN and ELSTON and CHRISTIAN et al. which utilizes all available information from twin data, was proposed and discussed. This estimate seems to be the least affected by fluctuations in the magnitudes of dominance and environmental variances.

摘要

利用Falconer方差成分模型,提出了一种将从双胞胎数据估计的遗传方差划分为加性方差和显性方差的方法。还回顾了显性方差和环境方差对一些遗传力估计值的影响。基于方差分析以及HASEMAN和ELSTON以及CHRISTIAN等人提出的遗传方差估计值,提出并讨论了一种利用双胞胎数据中所有可用信息的遗传力估计值。这种估计值似乎受显性方差和环境方差大小波动的影响最小。

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