水杨酸盐治疗期间的血清转氨酶
Serum transaminases during salicylate therapy.
作者信息
Russell A S, Sturge R A, Smith M A
出版信息
Br Med J. 1971 May 22;2(5759):428-9. doi: 10.1136/bmj.2.5759.428.
Abstract
In 8 out of 32 juvenile patients suffering from chronic polyarthritis and in one patient with dermatomyositis, raised transaminase levels were found; the salicylate level was above 35 mg/100 ml in all except one. Reduction in the salicylate level led to a prompt fall in the serum transaminases. Despite a rise in alkaline phosphatase in three cases there was no other evidence of liver dysfunction in the children. Only one of the adults showed a rise in transaminase levels, and she had mild cirrhosis.
摘要
在32名患有慢性多关节炎的青少年患者中，有8名以及1名皮肌炎患者的转氨酶水平升高；除1名患者外，所有患者的水杨酸盐水平均高于35mg/100ml。水杨酸盐水平降低导致血清转氨酶迅速下降。尽管有3例碱性磷酸酶升高，但这些儿童没有其他肝功能障碍的证据。只有1名成年人的转氨酶水平升高，她患有轻度肝硬化。
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