胰高血糖素在胰腺炎治疗中的可能用途。
Possible use of glucagon in the treatment of pancreatitis.
作者信息
Knight M J, Condon J R, Smith R
出版信息
Br Med J. 1971 May 22;2(5759):440-2. doi: 10.1136/bmj.2.5759.440.
Abstract
Four patients with pancreatic disease received glucagon intravenously. In two a definite decrease in the volume of pancreatic exocrine secretion was shown, and in one of these pancreatic juice protein and bicarbonate levels also fell. Two patients with acute pancreatitis had pronounced relief of epigastric pain associated with falls in plasma amylase after intravenous glucagon.Several mechanisms could account for the possible beneficial effect of glucagon in pancreatitis, and further studies of its use in this disease are justified.
摘要
4例胰腺疾病患者接受了静脉注射胰高血糖素治疗。其中2例显示胰腺外分泌量明显减少，且其中1例的胰液蛋白和碳酸氢盐水平也有所下降。2例急性胰腺炎患者在静脉注射胰高血糖素后，上腹部疼痛明显缓解，同时血浆淀粉酶水平下降。有几种机制可以解释胰高血糖素在胰腺炎中可能产生的有益作用，因此有必要对其在该疾病中的应用进行进一步研究。
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