Lee C, Katz R L
Anesth Analg. 1977 Mar-Apr;56(2):271-5.
Trains of neurally evoked compound electromyographic responses of the thenar muscles were studied in 20 patients anesthetized with enflurane and N2O and paralyzed with d-tubocurarine. Fade was correlated with stimulus frequency (0.1 to 50 Hz) and degree of neuromuscular block. The lowest response in a train occurred on the 4th and the 6th-to-8th responses when the train was elicited at 2 Hz and 50 Hz, respectively. Fade was more observable with deeper block and could best be demonstrated by 5 Hz stimuli. With 50 Hz stimuli, a concomitant facilitation, observable from the beginning of the train, partially compensated for the fade.
对20例用恩氟烷和氧化亚氮麻醉并使用右旋筒箭毒碱使其麻痹的患者，研究了神经诱发的大鱼际肌复合肌电图反应序列。衰减与刺激频率（0.1至50Hz）和神经肌肉阻滞程度相关。当分别以2Hz和50Hz诱发反应序列时，序列中的最低反应分别出现在第4个以及第6至第8个反应时。阻滞越深，衰减越明显，5Hz刺激能最好地显示这一点。对于50Hz刺激，从反应序列开始就能观察到的一种伴随的易化作用部分补偿了衰减。
